Secular Changes in Severity of Intellectual Disability in Tuberous Sclerosis Complex: A Reflection of Improved Identification and Treatment of Epileptic Spasms?
نویسندگان
چکیده
1Department of Child & Adolescent Psychiatry and MRC Social, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London 2Institute of Medical Genetics, Division of Cancer and Genetics, Cardiff University School of Medicine, Cardiff, UK 3Mental Health and Learning Disabilities division, Anuerin Bevan University Health Board, Newport, UK. 4Institute of Child Health, University College London, UK 5Department of Medical Genetics, University of Cambridge, Cambridge, UK
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INTRODUCTION Refractory epilepsy is a common clinical manifestation in patients with tuberous sclerosis complex (TSC), which can be complicated by many life-threatening conditions, such as status epilepticus (SE). However, very few reports mention the patterns and semiology of SE in those patients. OBJECTIVE To study the clinical characteristics and outcomes of SE in TSC patients. MATERIALS...
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تاریخ انتشار 2018